Dr Alexander Sobinoff’s field of research is cell biology, and he will be going to work every day for the next 12 months thanks to the funds provided by Fight on the Beaches.
His area of specialty is the the study of telomeres, tiny structures at the end of your DNA that protect it from being damaged. Over time these become so short they can no longer protect the DNA, causing the cell to die.Cancer cells, however, are unique in that they’re able to re-extend their telomeres, effectively becoming immortal. Dr Sobinoff aims to discover how they do this, in a quest for new drugs that inhibit the process.
As part of his grant, he will develop a rapid and reliable test to measure the length of telomeres, and then measure the effectiveness of drugs that inhibit telomere extension in the clinic.